CELNY
Hydroxypropyl Cellulose (HPC) is a water soluble, non-ionic derivative of cellulose, an abundant and natural polysaccharide found in all plants. CELNY™ brand is a high quality grade of HPC for food and nutraceutical use. CELNY is available in a wide range of viscosities and particle sizes to suit your application needs. It is food use approved globally, non-GMO, non-dairy, gluten and common allergen free. CELNY HPC applications include tablet binder, film forming agent, and stabilizer.
Our special low viscosity grades offer unique advantages for tablet formulations:
Excellent tablet hardness/friability with fast disintegration and active release times
Ease of use in wet granulation and coating applications
Highest compressibility at low usage level in dry binding applications
Features of CELNY
Highest efficiency tablet binder
Soluble in water and polar organic solvents
Nonionic, nonreactive, nontoxic
Eight different molecular weight grades produced designed for immediate or sustained release
Three different particle size grades tailored to wet or dry application
Minimal lot-to-lot variability enabling Quality By Design
Global regulatory approval in food and pharma
5-year shelf life
No additives such as silica
Physical and Chemicals Characteristics
Solution Characteristics
Viscosity vs. Solution Concentration (aq.)
Viscosity vs. Solution Concentration (ethanol)
Viscosity vs Temperature Curve
| Gelation Temperature | SSL-20% | SL-10% | L-8% | M-2% | H-1% | VH-1% |
|---|---|---|---|---|---|---|
| Temp.(℃) | 50 | 47 | 45 | 42 | 41 | 41 |
Thermal Cohesiveness
Moisture content over time
Effect of pH on HPC aqueous viscosity
2% solutions of HPC were measured at various pH at 20°C.
CELNY GRADES & APPLICATIONS
| NISSO HPC | SSL | SL | L | LM | LMM | M | H | VH | |
|---|---|---|---|---|---|---|---|---|---|
| Viscosity (mPa·s) 20℃/2% aq. solution | 2.0-2.9 | 3.0-5.9 | 6.0-10.0 | 11-20 | 21-50 | 150-400 | 1000-4000 | 4001-6000 | |
| Molecular Weight/GPC Method | 40,000 | 100,000 | 140,000 | 180,000 | 280,000 | 700,000 | 1,000,000 | 2,500,000 | |
| AVAILABILITY | Regular Powder (40 mesh pass) D50: 150-190 μm |  ＊ | | | | | | | |
| Fine Powder (100 mesh pass) D50: 80-110 μm | | | | | | ||||
| Super Fine Powder (330 mesh pass) D50: 20 μm | | ||||||||
| APPLICATION | High Shear Granulation  | ||||||||
| Fluidized Bed Granulation | |||||||||
| Direct Compression Dry Granulation
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| Hot Melt Processing | |||||||||
| Film Coating | |||||||||
| Solubility Enhancement | |||||||||
| Controlled Release Matrix Tablets | |||||||||
- General Information
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Applications
